Spatial transcriptomics (ST) technologies reveal the spatial organization of gene expression in tissues, providing critical insights into development, neurobiology, and cancer. However, the high cost ...

In a collaboration between several labs at UNC Lineberger, researchers have defined cancer-associated fibroblast (CAF) subtypes that are clinically robust, prognostic, and predictive of immunotherapy ...

The integration of single-cell and spatial transcriptomics with advanced metabolic profiling tools has revolutionized the ...

Immune checkpoint inhibitors and other immunotherapies/ cancer vaccines have revolutionised the oncology landscape, offering durable responses in cancers ...

Cancer tumors hijack the vagus nerve to communicate with the brain, triggering a hormonal response that suppresses the immune system.

What do healthy bone marrow cells in children look like? For the first time, researchers have mapped this out. Scientists at the Princess Máxima Center examined nearly 91,000 individual bone marrow ...

A new research paper was published in Volume 18 of Aging-US on February 8, 2026, titled "Single-cell transcriptomics reveal ...

Immunotherapy—which activates the body's own immune system to kill cancer cells—has not worked well against a rare and fatal liver cancer, but a new study finds an existing FDA-approved drug may allow ...

Initially, cells are dissociated from liver tissues into single-cell suspensions using in vivo enzymatic perfusion or ex vivo digestion methods. The cells of interest are then enriched from the ...