An ecosystem approach forces broader thinking. It requires cross-functional alignment and discourages short-term technical ...

ABSTRACT: With a panel data of Henan Province in China from 2014 to 2021, this study examines the role and mechanism of the digital economy on the integration of advanced manufacturing and modern ...

HBx plays a pivotal role in HBV replication by enhancing cccDNA transcription. However, the HBx structure remains unsolved, representing a significant gap in knowledge. Here, we show the cryo-EM ...

Target Discovery Institute, Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7FZ, U.K. ARUK-Oxford Drug Discovery Institute, Centre for Medicines ...

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Within the realm of scientific exploration, olfactory receptors constitute a prominent segment of the G-protein-coupled receptor (GPCR) superfamily, ranking among the most extensive protein families ...

Abstract: Traditional visual simultaneous localization and mapping (SLAM) methods excel in static, texture-rich environments, but may struggle in dynamic, textureless environments. Recent advances in ...

Under physiological conditions, proteins continuously undergo structural fluctuations on different timescales. Some conformations are only sparsely populated, but still play a key role in protein ...

Abstract: Recent advances in learning or identification of nonlinear dynamics focus on learning a suitable model within a pre-specified model class. However, a key difficulty that remains is the ...