MedLearn on Instagram: "Proton Pump Inhibitors (PPIs) are the most effective drugs for reducing gastric acid secretion. They act directly on the parietal cells of the stomach, where acid is produced. Inside the parietal cell membrane is an enzyme called H⁺/K⁺ ATPase, also known as the proton pump. This pump is responsible for the final and most important step of acid production. PPIs irreversibly inhibit this proton pump, which leads to a 90–95% reduction in acid secretion, regardless of whether